. Author manuscript; available in PMC: 2008 Oct 29.

Published in final edited form as: Cell Motil Cytoskeleton. 2006 Jan;63(1):14–28. doi: 10.1002/cm.20102

TABLE I.

Summary of Binding Data for PFN-1, PFN-2, and PFN-3

	K_d (μM)	C_50% (μM)	[Urea] (M)
PFN-1	2	14	3
PFN-2	2.4	15	5
PFN-3	3.4	7	5
Hum prof I	0.4^a	44^a	8^b
Rat prof IIa	0.4^a	155^a	8^b
Yeast prof	2.9^c	ND	ND

K_d indicates the equilibrium dissociation constant for actin; C_50%, the concentration of PI-4,5-P₂ for which 50% of profilin is bound to PI-4,5-P₂ micelles; and [Urea], the concentration of urea required for eluting profilin from the poly(l-proline) sepharose column during the purification procedure. ND indicates that these data are not available.

[Lambrechts et al., 2000a].

[Lambrechts et al., 1995].

[Eads et al., 1998].