. Author manuscript; available in PMC: 2008 Oct 29.

Published in final edited form as: Biochemistry. 2004 May 25;43(20):6064–6075. doi: 10.1021/bi0359574

Table 2.

PS of Aβ40, Aβ30, and Gd[N-4ab/Q-4ab]Aβ30 at the BBB in the Normal Adult Mouse (B6SJL)^a

brain region	Aβ40 (n = 14)	Aβ30 (n = 11)	RI	P	Gd[N-4ab/Q-4ab]Aβ30 (n = 6)	RI	P
cortex	52.3 ± 3.4	117.5 ± 4.7	2.2	^b	79.2 ± 4.1	1.5	^b
caudate-putamen	41.0 ± 3.2	101.8 ± 4.1	2.5	^b	65.8 ± 4.7	1.6	^c
hippocampus	48.7 ± 3.2	113.8 ± 5.2	2.3	^b	89.4 ± 6.2	1.8	^b
thalamus	50.8 ± 3.4	136.0 ± 6.1	2.7	^b	84.4 ± 3.8	1.7	^b
brain stem	61.6 ± 4.1	134.4 ± 6.1	2.2	^b	92.2 ± 5.9	1.5	^c
cerebellum	65.5 ± 4.5	131.9 ± 5.0	2.0	^b	102.8 ± 7.4	1.6	^b

PS is the product of the permeability coefficient and the surface area (×10⁻⁶ milliliters per gram per second, (x̄ ± SEM) determined over the course of 15 min. RI is the relative increase vs Aβ40. P is the ANOVA with Bonferroni multiple comparisons vs Aβ40.

P < 0.001.

P < 0.01.