Table 1.
Numbers of Ig light chain genes in 12 tetrapod species
| Species | κ |
λ |
σ |
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
IGVK |
IGJK |
IGCK |
Loc |
IGVL |
IGJL |
IGCL |
Loc |
IGVS |
IGJS |
IGCS |
Loc | ||||||||||
| F | P | F | P | F | P | F | P | F | P | F | P | F | P | F | P | F | P | ||||
| Human | 34 | 38 | 5 | 0 | 1 | 0 | Ch 2 | 32 | 42 | 4 [1] | 2 | 4 | 3 | Ch 22 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Mouse | 80 | 78 | 4 | 1 | 1 | 0 | Ch 6 | 3 | 0 | 4 | 0 | 4 | 0 | Ch 16 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Rat | 76 | 98 | 5 | 1 | 1 | 0 | Ch 4 | 8 | 2 | 2 | 1 | 2 [1] | 0 | Ch 11 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Dog | 16 | 9 | 5 | 0 | 1 | 0 | Ch 17 | 51 | 65 | 9 | 0 | 9 | 0 | Ch 26 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Microbat | 0 | 0 | 0 | 0 | 0 | 0 | — | 93 | 39 (7) | 7 | 1 (5) | 10 [1] | 0 (2) | — | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Cow | 9 | 13 | 4 | 1 | 1 | 0 | Ch 11 | 28 | 29 (1) | 2 [1] | 2 | 2 [1] | 2 | Ch 17 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Horse | 22 | 25 | 4 | 1 | 1 | 0 | Ch 15 | 25 | 20 | 4 [1] | 2 | 4 [1] | 2 | Ch 8 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Opossum | 76 | 48 | 4 | 1 | 1 | 0 | Ch 1 | 51 | 10 | 8 | 0 | 8 | 0 | Ch 3 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Platypus | 9 | 9 (1) | 6 | 1 | 1 | 0 | — | 14 | 7 (2) | 3 | 0 (1) | 3 | 0 (1) | — | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Chicken | 0 | 0 | 0 | 0 | 0 | 0 | — | 1 | 24 | 1 | 0 | 1 | 0 | Ch 15 | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Lizard | 13 | 3 | 4 | 0 | 1 | 0 | — | 29 | 9 | 2 | 1 | 2 [1] | 0 | — | 0 | 0 | 0 | 0 | 0 | 0 | — |
| Frog | 45 | 10 | 5 | 4 | 1 | 0 | — | 8 | 4 | 5 | 0 | 3 | 0 | — | 9 | 4 | 3 | 1 | 1 | 0 | — |
F, functional gene; P, pseudogene; Loc, location. The number in the parentheses is that of partial genes. In the λ locus, the IGJL-IGCL block can be nonfunctional if one of them is a pseudogene. The number in brackets indicates the IGJL or IGCL genes that are nonfunctional because the partner gene is defective.