Table 6.
Odds ratios (95% confidence interval) of prognostic factors among invasive breast cancers according to molecular phenotype, Nurses' Health Study (1976 to 1996)
Tumour type | Luminal A | Luminal B | Her2 type | Basal | Unclassified | |||||
n | OR | n | OR (95%CI) | n | OR (95%CI) | n | OR (95%CI) | n | OR (95%CI) | |
Tumour sizea,b | ||||||||||
≤ 2.0 cm | 1025 | 54 | 48 | 107 | 57 | |||||
>2.0 cm | 537 | 1.0 (Ref) | 55 | 1.9 (1.3 to 2.8) | 68 | 2.6 (1.8 to 3.9) | 119 | 2.0 (1.5 to 2.7) | 44 | 1.4 (0.9 to 2.1) |
Tumour gradea | ||||||||||
Low/Intermediate | 478 | 26 | 21 | 33 | 16 | |||||
High | 252 | 1.0 (Ref) | 20 | 1.4 (0.8 to 2.6) | 43 | 3.6 (2.1 to 6.3) | 99 | 5.3 (3.5 to 8.1) | 30 | 3.4 (1.8 to 6.4) |
Nodal statusa,b | ||||||||||
No nodes | 1103 | 72 | 61 | 145 | 70 | |||||
Any nodes | 547 | 1.0 (Ref) | 44 | 1.2 (0.8 to 1.7) | 67 | 2.1 (1.5 to 3.1) | 100 | 1.3 (1.0 to 1.7) | 40 | 1.1 (0.7 to 1.6) |
Menopausal status | ||||||||||
Postmenopausal | 1289 | 76 | 97 | 187 | 83 | |||||
Premenopausal | 334 | 1.0 (Ref) | 35 | 1.8 (1.2 to 2.7) | 27 | 1.1 (0.7 to 1.7) | 51 | 1.1 (0.8 to 1.5) | 25 | 1.2 (0.7 to 1.8) |
aAdjusted for age (five-year categories). bTumour characteristics abstracted from medical pathology reports. CI, confidence interval; OR, odds ratio.