Table 1.
Demographic data
| Parameters | Blood glucose 3.5 to 6.5 mmol/l | Blood glucose 5 to 8 mmol/l |
| Number of patients | 114 | 114 |
| Men (n [%]) | 87 (76%) | 87 (76%) |
| Women (n [%]) | 27 (24%) | 27 (24%) |
| Isolated TBI (n) | 40 | 40 |
| Multiple injuries (n) | 74 | 74 |
| Age (years; mean [range]) | 41 (18–81) | 38 (18–81) |
| AIS head (mean [range]) | 25 (9–36) | 25 (9–36) |
| AIS without head (mean [range]) | 16 (1–55) | 16 (1–55) |
| ISS (mean [range]) | 34 (16–54) | 34 (12–67) |
| Injured organs (n [range]) | 2 (1–5) | 2 (1–5) |
| Initial GCS (mean [range]) | 11 (3–15) | 10 (3–15) |
| CT lesions (n [%]) | ||
| EDH | 4 (3.5%) | 3 (2.6%) |
| SDH | 8 (7%) | 12 (10.5%) |
| Contusions | 15 (13.2%) | 15 (13.2%0 |
| Generalized oedema | 7 (6.1%) | 9 (7.9% |
| tSAH | 3 (2.6%) | 6 (5.3%) |
| mixed lesions | 77 (67.5%) | 69 (60.5%) |
| Surgery (%) | ||
| ICP probe | 100% | 100% |
| Fractures | 28% | 31% |
| Craniectomy | 4% | 4% |
| ICP > 20 mmHg (n [%]) | 27 (24%) | 33 (29%) |
| Nonsurvivors (n [%]) | 12 (41%) | 11 (50%) |
| Survivors (n [%]) | 22 (26%) | 17 (18%) |
| Arterial hypotension (SBP < 90 mmHg; n) | 1 | 1 |
| Mortality (n/n [%]) | 29/114 (25%) | 22/114 (19%) |
| Week 1 | 12/114 (11%) | 8/114 (7%) |
| Week 2 | 9/89 (10%) | 5/86 (6%) |
| Week 3 | 8/57 (14%) | 9/57 (16%) |
| ICU length (days; median [range]) | ||
| Survivors | 17 (2–48) | 15 (2–52) |
| Deceased | 9 (2–23) | 11 (2–43) |
Demographic data in 228 propensity-matched patients with severe traumatic brain injury (TBI) subjected to two different blood glucose targets: 3.5 to 6.5 mmol/l versus 5 to 8 mmol/l. AIS, abbreviated injury score; CT, computed tomography; EDH, epidural haematoma; GCS, Glasgow Coma Scale; ICP, intracranial pressure; ICU, intensive care unit; ISS, injury severity score; SDH, subdural haematoma; tSAH, traumatic subarachnoid haemorrhage; BP = blood pressure.