Table 3.
Trauma (n = 66) | AOX | Placebo | P value |
Number | 34 | 32 | |
Injury Severity Score, all | 30.1 ± 9.8 | 28.3 ± 10.4 | NS |
Brain injury (n = 39; 20/19) | 31.0 ± 11.0 | 28.7 ± 11.9 | NS |
No brain injury (n = 27; 14/13) | 28.9 ± 7.9 | 27.6 ± 8.1 | NS |
Injury Severity Score brain, in brain-injured | 14.5 ± 4.9 | 10.8 ± 4.5 | 0. 019 |
Glasgow Coma Scale score initial, all | 10.4 ± 4.9 | 11.8 ± 4.3 | 0.16 |
Brain injury | 7.4 ± 4.3 | 9.7 ± 4.8 | 0.11 |
No brain injury | 14.6 ± 0.6 | 14.8 ± 0.8 | NS |
SAPS II | 39.9 ± 17.0 | 31.1 ± 12.2 | 0.04 |
SOFA score, neuro section | 1.62 ± 1.7 | 0.97 ± 1.2 | 0.085 |
Brain injury | 2.5 ± 1.6 | 1.38 ± 1.2 | 0.012 |
No brain injury | 0.2 ± 0.4 | 0.2 ± 0.6 | NS |
Data are presented as mean ± standard deviation. P values refer to comparison between the antioxidant (AOX) and placebo groups. NS, not significant; SAPS, Simplified Acute Physiology Score; SOFA, sequential organ failure assessment.