Table 2.
Physiologic conditions at the beginning and the end of ventilation
| Nonventilated room air | 6 ml/kg tidal volume room air | 30 ml/kg tidal volume room air | |
| PH | 7.40 ± 0.05 | 7.35 ± 0.02 | 7.33 ± 0.06 |
| Arterial oxygen pressure (mmHg) | 98.7 ± 0.6 | 82.3 ± 7.5 | 86.1 ± 1.3 |
| Arterial carbon dioxide pressure (mmHg) | 40.2 ± 0.5 | 39.1 ± 1.1 | 35.3 ± 1.9 |
| Mean arterial pressure (mmHg) | |||
| Start | 86 ± 1.9 | 85.3 ± 3.0 | 84.6 ± 2.3 |
| End | 85 ± 0.8 | 81.3 ± 2.2 | 73.5 ± 7.1 |
| Peak inspiratory pressure (mmHg) | |||
| Start | 9.5 ± 1.5 | 23.6 ± 2.6 | |
| End | 11.7 ± 1.8 | 27.9 ± 3.8 |
Arterial blood gases and mean arterial pressure of normal nonventilated mice and of mice ventilated at tidal volumes of 6 ml/kg or 30 ml/kg for 5 hours (n = 10 per group).