Figure 3.

Poly (ADP-ribose) polymerase (PARP) activity assay. Larger numbers of positively stained cells were observed in the ventilator-induced lung injury (VILI) group (c) than in the other groups. Positive cells were almost completely absent in the sham (a), lung-protective ventilation (LPV) (b), and PJ34+VILI (d) groups. The number of cells with PARP activity (e) in five high-power fields (HPFs) (× 400) was higher in the VILI group (*P < 0.05) than in the other groups, with significant differences among the four groups (P = 0.002 by the Kruskal-Wallis test).