Table 2.
Clinical procedures
| UFH (n = 20) | UFH + tirofiban (n = 20) | P value | |
| Cardiac procedures | |||
| Coronary angiography, number | 18 | 19 | 0.560 |
| Percutaneous coronary intervention, number | 15 | 18 | 0.560 |
| Intra-aortic balloon pump, number | 11 | 12 | 0.876 |
| Intra-aortic balloon pump duration in hours, mean ± SD | 48 ± 14.4 | 50 ± 12.5 | 0.757 |
| Haemodialysis characteristics | |||
| Treatment dose in mL/kg per hour, mean ± SD | 28 ± 2.5 | 28 ± 2.9 | 0.381 |
| Blood urea nitrogen (BUN) | |||
| Pretreatment BUN in mg/dL, mean ± SD | 72 ± 23.3 | 70 ± 24.1 | 0.734 |
| Steady-state BUN during CRRT in mg/dL, mean ± SD | 32 ± 18.1 | 31 ± 22.1 | 0.734 |
| Antiplatelet therapy and anticoagulation | |||
| No antiplatelets, number | 3 | 1 | - |
| Acetylsalicylic acid alone, number | 2 | 1 | - |
| Acetylsalicylic acid and thienopyridine, number | 15 | 18 | - |
| UFH, number (dose in IU/kg per hour, mean ± SD) | 20 (18.4 ± 0.6) | 20 (18.2 ± 0.8) | 0.872 |
| Activated partial thromboplastin time in seconds, mean ± SD | 64 ± 13.2 | 62 ± 11.8 | 0.621 |
| Ivy bleeding time in seconds, mean ± SD | 422 ± 58.1 | 599 ± 118.1 | 0.003 |
| Further concomitant therapy | |||
| Dobutamine, number (dose in μg/kg per minute, mean ± SD) | 18 (6 ± 2.8) | 19 (6 ± 3.2) | 0.560 |
| Norepinephrine, number (dose in μg/kg per minute, mean ± SD) | 14 (0.2 ± 0.1) | 13 (0.2 ± 0.15) | 0.744 |
| Opioids and benzodiazepins, number | 12 | 14 | 0.519 |
| Mechanical ventilation, number | 12 | 14 | 0.519 |
CRRT, continuous renal replacement therapy; SD, standard deviation; UFH, unfractioned heparin.