Table 2.
Histological grading of proteoglycan extracellular matrix formation by adipose-derived mesenchymal stem cells (AD-MSC) seeded into 3D matrixa
| Age of donor sand rat | Number of weeks of cultured | Mean histological grading score (mean +/- standard deviation) | |
| - TGFβ | + TGFβb | ||
| 10 weeks | 3 to 5 | 2.0 ± 0.0 (3) | 3.0 ± 0.0 (3) |
| 6 months | 3 to 6 | 1.0 ± 0.0 (3) | 2.7 ± 0.47 (3) |
| 20 months | 3 to 4 | 1.3 (2) | 3.3 (2) |
aScoring scale: 0 = no localization; 1 = very slight localization; 2 = modest localization; 3 = abundant localisation. bTransforming growth factor beta (TGFβ) treated AD-MSC gave a significantly higher score compared with untreated cells (p < 0.05).