Table 3. Clinical Outcomes.
Outcome | Confirm+ (n=98) | Confirm- (n=17) | |||
---|---|---|---|---|---|
HIT+
(n=56) |
HIT?
(n=15) |
HIT-
(n=27) |
HIT+/HIT?
(n=3) |
HIT-
(n=14) |
|
Thromboembolic event (HITT; n=32) | 26 (46%) | 6 (40%) | 0 | 0 | 0 |
Treated with a DTI (n=50) | 41/56 (73%) | 4/15 (27%) | 1/27 (4%) | 3/3 (100%) | 1/14 (7%) |
Isolated HIT patients | 18/30 (60%) | 0 | - | 3/3 (100%) | 0 |
HIT with thrombosis patients | 23/26 (88%) | 4/6 (67%) | - | 0 | 0 |
Hemorrhagic complication * | 11/41 (27%) | 2/4 (50%) | 0 | 1/3 (33%) | 0 |
Thromboembolic event * | 3/41 (7%) | 0 | 1/27 (4%) | 2/3 (66%) | 1/14 (7%) |
Death * | 9/41 (22%) | 2/4 (50%) | 1/27 (4%) | 1 (33%) | 0 |
Not treated with a DTI (n=65) | 15/56 (27%) | 11/15 (73%) | 26/27 (96%) | 0 | 13/14 (93%) |
Hemorrhagic complications | 2/15 (13%) | 1/11 (9%) | 8/26 (31%) | - | 3/14 (21%) |
Thromboembolic complications | 2/15 (13%) | 2/11 (18%) | 4/26 (15%) | - | 7/14 (50%) |
Death | 3/15 (20%) | 2/11 (18%) | 4/26 (15%) | - | 2/14 (14%) |
Clinical events occurring after diagnosis of HIT initially made. These events may have occurred while the patient was on a DTI, or after the DTI had been discontinued.