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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Mol Microbiol. 2008 Mar 4;68(3):749–767. doi: 10.1111/j.1365-2958.2008.06188.x

Fig. 8. Inhibition of ROCK activity increases virulence in mice and is dependent on expression of InlF.

Fig. 8

Groups of seven BALB/c mice were injected intravenously (i.v.) with 10 mg/kg HA-1077 (+) or PBS (-) and 5 h later infected via i.v. injection with wild-type 10403S (WT) or ΔinlF bacteria (1×104 bacteria/animal). At 72 h post-infection, the bacterial burden in the liver and spleen was determined. Each symbol represents the CFU per organ of one mouse. Horizontal bar indicates the mean value per group. p, represents the statistical significance between bracketed groups.