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. 2008 Nov 3;183(3):513–526. doi: 10.1083/jcb.200804048

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Figure 10. — Schematic representation of the regulation of retromer by Rab5 and Rab7. The scheme depicts a section of an endosome with its vacuolar and tubular aspects. The sequence of reactions is represented in the context of the progression from Rab5- to Rab7-positive endosomes and from the vacuolar to the tubular aspect. Details of this model are described in the Discussion section. BAR, Bin–Amphiphysin–Rvs; HOPS, homotypic fusion and vacuole protein sorting; PX, phox homology.