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. Author manuscript; available in PMC: 2009 Aug 13.
Published in final edited form as: J Neuroimmunol. 2008 Jun 27;199(1-2):75–82. doi: 10.1016/j.jneuroim.2008.05.009

Figure 2. Pre-treatment with Pam3CSK4 preserved neurological function (A), reduced brain edema (B) and decreased mortality (C) following cerebral I/R.

Figure 2

Mice that were treated with (Pam-I/R) and without (I/R) Pam3CSK4 were subjected to ischemia (1 hr)/reperfusion (24 hrs). Respective sham surgical operated mice served as sham (S) and Pam-sham (Pam-S) controls. (A) Neurological function was evaluated using a scoring system ranging 0 to 15, with 15 being a perfect score and 0 being death due to cerebral I/R. (B) Brain water content was measured in cerebral tissues from the left hemisphere. (C) Mortality was monitored during reperfusion (within 24 hrs). The data are expressed as mean ± standard error (s.e.). *compared with sham; #compared with I/R, p<0.05.