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. Author manuscript; available in PMC: 2009 Aug 13.
Published in final edited form as: J Neuroimmunol. 2008 Jun 27;199(1-2):75–82. doi: 10.1016/j.jneuroim.2008.05.009

Figure 3. Pre-treatment with Pam3CSK4 preserved Blood Brain Barrier (BBB) function following cerebral I/R.

Figure 3

Mice that were treated with and without Pam3CSK4 were subjected to ischemia (1 hr) followed by reperfusion (24 hrs). Respective sham surgical operated mice served as sham (S) and Pam3CSK4 treated sham (Pam-S) controls. (A) Serum albumin in cerebral tissue was examined by Western blot. (B) Blood-brain barrier permeability was determined using the Evans Blue dye exudation method. Representative Evans Blue dye in brains is shown above the graph. The data are expressed as mean ± standard error (s.e.). *compared with sham, p<0.01; #compared with I/R, p<0.05.