Table 1.
Group | nt1* | nt2* | Pair* | Log2 doublet propensity | |
---|---|---|---|---|---|
G-1 | −30 | 9 | (C–G) | 0.94 | Watson–Crick pair |
−25 | −24 | (G–G) | 0.92 | ||
−22 | (G–G) | 1.02 | |||
−22 | −21 | (C–C) | 1.01 | ||
−10 | 5 | (G–C) | 0.92 | Watson–Crick pair | |
6 | (C–C) | 0.90 | |||
−3 | −2 | (C–G) | 0.92 | Watson–Crick pair | |
G-2 | −25 | −10 | (C–C) | 0.94 | |
G-3 | −16 | 5 | (G–G) | 0.95 | |
−10 | −5 | (C–C) | 0.91 | ||
6 | 8 | (G–G) | 0.93 | ||
G-4 | −28 | −25 | (C–G) | 1.07 | Watson–Crick pair |
−27 | 4 | (C–A) | 0.99 | ||
5 | (C–G) | 0.90 | Watson–Crick pair | ||
−26 | 10 | (C–C) | 0.91 | ||
−25 | −9 | (G–A) | 0.91 | ||
−21 | −5 | (C–C) | 0.99 | ||
−19 | 4 | (A–C) | 1.01 | ||
5 | (A–A) | 0.96 | |||
−15 | 5 | (A–A) | 1.05 | ||
−9 | 2 | (A–C) | 0.95 | ||
−8 | 5 | (G–G) | 0.94 | ||
−6 | 9 | (C–C) | 0.94 | ||
−2 | 5 | (A–G) | 0.92 | ||
1 | 10 | (A–C) | 0.91 | ||
4 | 5 | (C–A) | 0.94 | ||
G-5 | −27 | 5 | (C–G) | 0.90 | Watson–Crick pair |
−26 | −16 | (C–C) | 0.98 | ||
−24 | −16 | (G–G) | 0.98 | ||
−22 | 2 | (A–C) | 1.01 | ||
−21 | −20 | (C–C) | 0.96 | ||
−16 | −14 | (C–C) | 1.05 | ||
−15 | −8 | (C–G) | 0.90 | Watson–Crick pair | |
−13 | −9 | (G–A) | 0.97 | ||
3 | 8 | (A–C) | 1.02 | ||
G-6 | −29 | −13 | (G–G) | 0.90 | |
−23 | −15 | (C–G) | 0.94 | Watson–Crick pair | |
−22 | −6 | (C–G) | 0.93 | Watson–Crick pair | |
−20 | −14 | (C–C) | 0.95 | ||
−4 | (C–T) | 0.95 | |||
−18 | 6 | (C–C) | 0.92 | ||
−13 | 3 | (C–C) | 1.21 | ||
−8 | −3 | (G–C) | 0.98 | Watson–Crick pair | |
−3 | 4 | (C–A) | 0.96 | ||
7 | (C–A) | 1.06 | |||
G-7 | −27 | −15 | (G–G) | 0.96 | |
−9 | (C–G) | 0.95 | Watson–Crick pair | ||
−18 | 9 | (C–G) | 0.92 | Watson–Crick pair | |
G-8 | −27 | −6 | (A–C) | 0.97 | |
−26 | −15 | (C–G) | 0.92 | Watson–Crick pair | |
−24 | −17 | (G–C) | 0.92 | Watson–Crick pair | |
3 | (G–C) | 1.00 | Watson–Crick pair | ||
−23 | −8 | (G–G) | 1.01 | ||
−21 | −2 | (G–C) | 0.91 | Watson–Crick pair | |
−17 | −16 | (G–C) | 0.93 | Watson–Crick pair | |
3 | (G–G) | 1.06 | |||
8 | (G–G) | 0.91 | |||
−15 | 2 | (G–G) | 0.91 | ||
−14 | 4 | (G–G) | 0.92 | ||
−13 | 2 | (G–G) | 0.91 | ||
4 | (G–G) | 1.03 | |||
−6 | 8 | (C–G) | 1.06 | Watson–Crick pair | |
−2 | 8 | (T–G) | 0.97 | ||
2 | 5 | (C–A) | 0.93 | ||
8 | (G–G) | 1.02 |
*The statistically significant nucleotide pair in the parentheses appears at positions nt1 and nt2, respectively. We used the following rule of numbering nucleotide positions; position of the edited C was defined as 0, the nucleotides located on the 3′ side of the edited C had positive numbers and the nucleotides located on the 5′ side had negative numbers based on the distance in nucleotides from the C.