Table 5.
Myocardial structure and function in ad libitum- and pair-fed control and HIV Tg rats
|
Control |
HIV-1 Tg | ||
|---|---|---|---|
| Ad Libitum-Fed | Pair-Fed | ||
| LV systolic dimension, mm | 1.41±0.18* | 1.43±0.22* | 0.86±0.11† |
| LV diastolic dimension, mm | 6.44±40 | 6.29±0.39 | 5.91±0.22 |
| LVPW thickness, mm | 2.20±0.11 | 2.21±0.16 | 2.15±0.18 |
| IVS dimension, mm | 1.90±0.05* | 1.89±0.06* | 1.61±0.06† |
| IVS/LVPW | 0.85±0.04 | 0.87±0.05 | 0.79±0.06 |
| LV stroke volume, ml | 0.71±0.06* | 0.66±0.05* | 0.49±0.05† |
| Heart rate, beats/min | 335±23* | 334±21* | 398±10† |
| Cardiac output | |||
| ml/min | 234±26 | 214±28 | 198±21 |
| ml·min−1·g heart−1 | 217±32 | 228±31 | 240±29 |
Values are means ± SE of 6 ad libitum-fed control, 12 pair-fed control, and 14 HIV-1 Tg rats. LV, left ventricle; LVPW, LV posterior wall; IVS, intraventricular septum. Means without a common symbol ( *, †) are significantly different (P < 0.05).