Figure 3.

ODC localization in NHEK and in human dermal fibroblasts. To determine the effects of different cytoskeletal systems on ODC organization, NHEK (A) that contain a keratin intermediate filament system and fibroblasts (B) that contain a vimentin intermediate filament network were compared. The NHEK showed a predominately nuclear/perinuclear localization for ODC; the fibroblasts showed ODC staining throughout the cell. Digital micrographs were collected on a Bio-Rad confocal microscope. Bar, 10 μm.