Fig. 10.

Sensitization of low-threshold stretch-sensitive unit by bradykinin in Ca²⁺-free Krebs solution. A: mechanoreceptor responses to 3 mm stretch of 10 s duration in Ca²⁺-free Krebs solution (containing 3.6 mM Mg²⁺). B: 1 μM bradykinin potentiated response of low-threshold mechanoreceptor to 3-mm stretch. Such effects were seen in 6 of 9 units tested. C: pooled data (n = 6) show that the effect of bradykinin was statistically significant (*P = 0.0038, paired t-test).