Table 2.

r² values for differentially expressed genes within 4q21-q41 region on chromosome 4 in F344, LEW, COP, and DA rats

Candidate Genes	Location	Neck Width, mm	Neck Total vBMD, mg/cm3	Neck Total Area, mm2	Neck Trabecular Area, mm2	Neck Ip, mm4
Pdia4, protein disulfide isomerase associated 4	4q24	0.98	0.90	0.81	0.98	0.84
Igf2bp3, insulin-like growth factor 2, binding protein 3	4q24	0.96	0.80	0.73	0.81	0.72
Aqp1, aquaporin 1	4q24	0.96	0.95	0.89	0.95	0.90
Vps24, vacuolar protein sorting 24	4q33	0.96	0.74	0.63	0.96	0.66
Gimap4, GTPase, IMAP family member 4	4q24	0.93	0.62	0.53	0.76	0.52
Fscn3, fascin homolog 3, actin-bundling protein, testicular	4q22	0.93	0.67	0.60	0.74	0.58
Spr, sepiapterin reductase	4q34	0.92	0.71	0.65	0.72	0.62
St3gal5, ST3 β-galactoside α-2,3-sialyltransferase 5	4q33	0.91	0.57	0.48	0.74	0.47
Lr8, LR8 protein	4q24	0.91	0.58	0.46	0.85	0.48
Snx10, sorting nexin 10	4q24	0.88	0.65	0.60	0.66	0.57
Nr2c2, nuclear receptor subfamily 2, group C, member 2	4q34	0.87	0.49	0.39	0.74	0.40
Chchd4, coiled-coil-helix-coiled-coil-helix domain containing 4	4q34	0.85	0.54	0.42	0.85	0.45
Serbp1, serpine1 mRNA binding protein 1	4q31	0.77	0.86	0.79	0.94	0.84
Gpnmb, glycoprotein (transmembrane) nmb	4q24	0.69	0.96	0.99	0.69	0.97
Ptprz1, protein tyrosine phosphatase, receptor-type, Z polypeptide 1	4q22	0.60	0.80	0.86	0.49	0.80
Copg, coatomer protein complex, subunit-γ	4q34	0.60	0.23	0.14	0.57	0.16
Arl6ip5, ADP-ribosylation factor-like 6 interacting protein 5	4q34	0.53	0.18	0.13	0.30	0.11
Gmcl1, germ cell-less homolog 1	4q34	0.52	0.25	0.15	0.62	0.20