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Forearm blood flow (FBF) responses to intrabrachial artery infusion of acetylcholine (i.e., endothelium-dependent dilation) in sedentary (left) and endurance exercise-trained (middle) healthy young and middle-aged/older men, and before and after an aerobic exercise intervention in middle-aged/older men (right). *P < 0.05. [From DeSouza et al. (17).]
