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. 2008 Aug 14;105(4):1127–1133. doi: 10.1152/japplphysiol.00117.2008

Fig. 1.

Fig. 1.

Changes in total pulmonary resistance (RL) (A), airway resistance (Raw) (B), and the coefficient of lung tissue damping (G) (C) induced by intravenous methacholine in wild-type (WT) and db/db mice. Mice were treated by gavage with water or metformin once per day for 2 wk. Measurements were made 24 h after the last treatment. Results are means ± SE of data from 6–7 mice in each group. *P < 0.05 vs. WT mice in the same treatment group.