Table 1.

Baseline measurements of total pulmonary, airway, and parenchymal mechanics in obese db/db and lean wild-type mice treated with water or metformin

	Body Mass, g	RL, cmH2O·ml−1·s	Raw, cmH2O·ml−1·s	G, cmH2O/ml	H, cmH2O/ml
WT
Water	26.7±1.7	0.50±0.02	0.22±0.02	2.78±0.14	17.3±0.4
Metformin	26.0±1.4	0.51±0.03	0.25±0.02	2.54±0.17	18.7±1.3
db/db
Water	60.8±1.4*	0.62±0.02*	0.26±0.02	3.52±0.26*	23.3±1.3*
Metformin	62.0±1.6*	0.58±0.02*	0.23±0.02	3.69±0.29*	22.3±1.1*

Values are means ± SE. Measurements were made 24 h after the last gavage treatment. R_L, lung resistance; Raw, airway resistance; G, coefficient of lung tissue damping; H, coefficient of lung tissue elastance.

^*P < 0.05 compared with wild-type (WT) mice with same exposure.