Fig. 1.

Effects of repeated cycles of 5-day access to Chow A/I (C phase) alternated with 2-day access (P phase) to either Chow A/I (Chow A/I / Chow A/I, n = 14) or highly preferred chocolate-flavored sugary diet (Chow A/I / Preferred, n = 15) in male Wistar rats. A: average daily food intake. B: cumulative food intake (note that error bars are smaller than symbols). C: time course of food intake during 2 days of access to the preferred diet. Food intake was measured 1, 3, 6, 24, and 48 h after restoration of preferred diet access after 20 wk of diet cycling. Inset depicts food intake of the first (0–24 h) vs. second (24–48 h) day of access to preferred diet. Inset scale differs from main panel. D: average daily change in body weight during each diet phase of each week. *Significant difference from Chow A/I / Chow A/I, P < 0.05, **P < 0.01, ***P < 0.001.