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Inhibition of TR (2 μM) accumulation in rat CP at steady state by estrone sulfate (ES; A), taurocholate (TC; B), MK571 (C), and methotrexate (MTX; D). Values are means ± SE for tissue from 4–8 animals. *Significantly different from control, P < 0.05; **significantly different from control, P < 0.01. MK571, Mrp1 inhibitor.
