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. 2008 Oct 6;6:42. doi: 10.1186/1741-7007-6-42

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Copyright © 2008 Thomas and Robertson; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Negative correlation between orthology and nonfunctional gene frequencies in Caenorhabditis elegans. Each of the 19 gene families is plotted once. The X-axis is the fraction of C. elegans genes in the family with single orthologs in both C. briggsae and C. remanei. The Y-axis is the fraction of C. elegans genes in the family with probable defective alleles in the N2 reference genome sequence. The correlation shown is much stronger than that between family size and fraction of defective genes (see Additional file 9). R is the Pearson correlation coefficient.