Table 1.

Networks generated from IPA for focus genes that are up-regulated in MII^NSN oocytes when compared to MII^SN oocytes.*

Network	Genes in network	Score	Focus genes	Top functions
1	Akt, Anxa2, Bhlhb2, Calpain, Crkl, Glb1, Hoxa7, Insulin, Integrin, Lasp1, Ldl, Mcl1, Mdh2, Mfn2, Nadh2 Dehydrogenase, Nadh2 Dehydrogenase (Ubiquinone), Ndufa1, Ndufa3, Ndufv1, Pdgf Bb, Pi3k, Pik3c3, Pkc(S), Pp2a, Ptpn1, Rac, Rpl27a, Rps6, Rps18, Slc3a2, Smg5, Strn3, Tmsb10, Tsc2, Tspan3	42	23	Cancer, Immunological Disease, Tumor Morphology
2	Bat3, Bcas3, Calmodulin, Crkrs, Egfr, Helz, Histone H3, Hsp70, Ing1, Invs, Iqgap1(Includes Eg:8826), Map3k12, Msse, Nbpf15, Nelf, Nr2e1, P38 Mapk, Polr2l (Includes Eg:5441), Prkg1, Ranbp1, Rap1, Rbm16, Rna Polymerase Ii, Setd2, Slc9a8, Smn1, Spag7, Spt1, Tarbp1, Terf2ip, Tgf Beta, Ubc, Uqcrb, Uqcrc1, Wdr36	26	16	Post-Translational Modification, Cancer, Genetic Disorder
3	Abpa (Includes Eg:11354), Amino Acids, Arrb2, Cebpa, Clta, Cltb, Ddx21, Eef1a2, Farp2, Fntb, Glipr1, Grasp, Grin3b, Grina, H1fx, Ifitm2, Insr, Mark3, Myo6, Nmda Receptor, Nusap1, Paip2, Pfkfb3, Pim1, Prkx, Sag, Snrk, Src, Stk38, Stk17a, Tfam, Tk2, Tp53, Tp53rk, Vegf	22	14	Amino Acid Metabolism, Post-Translational Modification, Small Molecule Biochemistry
4	Afg3l2, Arl2, Atf7ip, Atox1, Atp13a2, Atp13a5, Atp5a1, Atp6v0a1, Atp6v0b, Atp6v0e2, Atp6v1c2, Atp6v1d, Atp6v1e2, Atp6v1g2, Atp6v1h, Atpase, Ddx19b, Ddx3y (Includes Eg:26900), Dqx1, Eif3a, Eif3f, Eif3j, Eif4e, Gtp, H+-Transporting Two-Sector Atpase, Lsm10 (Includes Eg:84967), Mlh1, Psmc4, Psmc5, Psmd7, Ralbp1, Rfc4, Rsf1, Spast, Tcirg1	22	14	Molecular Transport, Protein Synthesis, Gene Expression
5	Acaa2, Acaa1b, Acsl4, Alad, Bcat1, Cidec, Cpt2, Ddx11, Dleu1, Dleu2, Dnmt3l, E2f1, Emp1, Erbb2, Exosc9, Fng, Glg1, Gtf3c2, Hdac1 (Includes Eg:3065), Hn1, Lxn, Mfap1, Mfng, Myc, Notch1, Psat1, Rfng, Rps16, Rps20, Snrpn, Sycp3, Tbp, Tle4, Tmem126a, Uxt	20	13	Cancer, Dermatological Diseases and Conditions, Cell Cycle
6	Aars, Arsb, Arsd, Arse, Arsf, Arsg, Arsi, Arsj, Cct5, Cxcl12, Cxcr6 (Includes Eg:10663), Eif4h, Gns, Golga3, Hsd17b10, Kdelr2, Loxl2, Nsdhl, Pls3, Pth, Rab33b, Rbm14, Rdh11, Sec61a1, Sec61g, Slc34a1, Slc34a2, Srebf1, Ssr2, Stch, Sulf2, Sumf1, Syvn1, Tgfb1, Xbp1	20	13	Tissue Development, Tissue Morphology, Cellular Function and Maintenance
7	Abtb1, Actin Alpha-Ca2+-Myosin-Tropomyosin-Troponinc-Troponin I-Troponin T, Adcy9, Beta-Estradiol, Ca2+, Clec3b, Cnn3, Fn1, Ifi30, Igf1, Kcnn2, Mek1/2, Myh2, Nmur2, Nudt1, Pcna, Pdlim2, Pfkl, Pkia, Pla2g12a, Pla2g2d, Plg, Poldip2, Psma2, Psmb2, Psmd6, Psmd14, Pten, S100a2, Saps2, Serpinb12, Slc6a9, Spint1, Trpv2, Tsta3	18	12	Cancer, Cellular Growth and Proliferation, Reproductive System Disease
8	Alp, Aprt, Atp1a3, Atp5l, Bmp2, Chgb, Cox7a1, Creb1, Esd, Fgf7, Fos, Foxm1, Gfra1, Hcg 25371, Hgs, Hr, Klf3, Me1, Myo5b, Nfe2l2, Nkx6-2, Nudt7, Pgd, Phyh, Psmc3ip, Punc, Rxrb, Smarcd2, Tcea3, Thrb, Thyroid Hormone, Trim3, Trip4, Trip11, Ttf1	16	11	Gene Expression, Connective Tissue Development and Function, Cellular Development
9	Anapc5, Aptx, Cdca5, Cdca7l, Cdkn2a, Ctbp2, Ddx55, Deaf1, Epb42, Gypa, Icos, Ipo13, Ldb1, Lmo2, Lmo4, Mdm4, Nfkbib, Nhlh1, Nr3c1, P1, P4-Di(Adenosine-5') Tetraphosphate, Pdcd2, Pex3, Pex19, Plagl1, Rpl5, Sae1, Skp1, Smad2/3-Smad4, Sod2, Tcf3, Tfap2b, Tfap2c, Tgif1, Ube2i, Zp2	14	10	Gene Expression, Cell Cycle, Skeletal and Muscular System Development and Function
10	C4bpa, Foxj2	2	1	Cell-To-Cell Signaling and Interaction, Hematological System Development and Function, Tissue Development

*: in bold are Oct-4-regulated genes (see below).