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. 2008 Jul 16;100(4):2348–2360. doi: 10.1152/jn.90396.2008

FIG. 4.

FIG. 4.

Firing pattern in basket cells from monkeys and rats. A: firing patterns produced by monkey and rat basket cells in response to the current steps of different intensities. Note that the firing pattern in rats was characterized by the presence of quiescent periods. B: plot of coefficient of variation of interspike intervals (CV ISIs) vs. current intensity demonstrates more variability in ISIs in rat basket cells (n = 28) than that in monkey basket cells (n = 31). The difference was more substantial for the responses evoked by the near-threshold current intensities. Error bars represent SE. Asterisks indicate P < 0.05. C: number of spikes evoked in monkeys (n = 20) was considerably larger than that in rats (n = 18) for the near-threshold current intensities. Error bars represent SE. Asterisks indicate P < 0.05. D: application of α-DTX (150–200 nM) eliminated quiescent periods in rat firing pattern (n = 5).