Figure 10.

Model for the role of 95F myosin during individualization. 95F myosin (myosin VI; purple) functions during individualization to recruit vesicles (green circles) to the actin-rich cortex underlying the spermatid plasma membrane. 95F myosin transports vesicles a short distance along these actin filaments to the advancing edge of the investment cone. Once the vesicles arrive, they are incorporated into the remodeled membrane, which will enclose each sperm. The accumulation of 95F myosin-rich vesicles at the site of incorporation leads to 95F myosin enrichment in a ring at the base of the actin cone.