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Quantitation of the effect of 95F myosin mutations on IC organization. Each IC was scored as either colocalizing with nuclei or progressed away from nuclei and then as intact or disrupted. The determination of whether an IC was intact or disrupted was by examining whether the individual investment cones were scattered (disrupted) or lined up in register with one another (intact). The majority of wild-type ICs are intact. In contrast, the majority of the mutant ICs are disrupted.
