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. 2008 Jul 30;100(4):1936–1948. doi: 10.1152/jn.90290.2008

FIG. 4.

FIG. 4.

The ability of ifenprodil or NVP-AAM077 to block LTP in the visual cortex is age-dependent. A: in juvenile animals (P21-28), LTP is significantly attenuated by either ifenprodil or NVP-AAM077. B: in adult animals (P45-90), 50 nM NVP-AAM077 completely blocks LTP, whereas 3 μM ifenprodil has no effect on its magnitude. In both panels, the traces shown above each plot are averages of the 15 min baseline and the last 15 min poststimulation of a representative recording under control conditions.