Figure 2.
Divergence between TEP1s and TEP1r alleles. The proportion of sites that differ between the TEP1s and TEP1r alleles are plotted against position for all silent sites, synonymous sites, and non-synonymous sites). Genomic sequence spanned by the macroglobulin domains 1–8 (MG), a linker (LNK), a β-sheet and the thioester-containing domain (TED) are marked below the x-axis. Also marked are exons (solid black bars) and a region of putative gene conversion from TEP6 (grey bar, see main text for details). For zero to 5 kbp, 14 TEP1s and 15 TEP1r haplotypes were used; for 5 kbp to end, 6 TEP1s and 5 TEP1r haplotypes were used. Moving windows were 100-site for silent and synonymous sites, 300-site for non-synonymous sites and gaps in Ksilent correspond to regions with large indels and/or no discernable alignment between TEP1s and TEP1r haplotypes.