Figure 8.

Complex losses and gains in the q-arm of Chr:16 of sample C111. The figure shows the LR from the 500 K (top) and 19 K BAC (bottom) arrays with the genomic scale (x-axis) indicating the SNP position or the center point of the BAC clone. The status of the CN changes is more clearly resolved with the 500 K arrays than with the BAC array, particularly for two sizeable regions of loss (between 45 Mb-54 Mb and 59 Mb – 63 Mb). Furthermore, CGH does not clearly detect a loss at 20.88 – 23.36 Mb and a copy neutral region within a deletion at 77.14 – 77.54 Mb (arrows).