Table 2.

Effect of Intermittent PTH(1-34) on Tibial Bone

		C57BL/6			LDLR-/-
		Vehicle (n = 7)	PTH (n = 7)	Percent change	Vehicle (n = 7)	PTH (n = 9)	Percent change
BMD (mg/cm3)	Total	729 ± 7.9	779 ± 14*	+6.8	729 ± 13	729 ± 7.6
	Cortical	1073 ± 6.4	1117 ± 9.5†	+4.1	1073 ± 7.2	1079 ± 6.7
	Trabecular	76.2 ± 6.8	88.6 ± 5.3		85.6 ± 6.3	85.6 ± 6.7
BMC (mg/mm)	Total	1.05 ± 0.025	1.15 ± 0.028*	+9.6	1.02 ± 0.027	1.03 ± 0.022
	Cortical	0.870 ± 0.024	0.985 ± 0.030*	+13	0.849 ± 0.026	0.860 ± 0.021
	Trabecular	0.033 ± 0.003	0.031 ± 0.003		0.031 ± 0.003	0.031 ± 0.03
Area (mm2)	Total	1.46 ± 0.022	1.49 ± 0.026		1.42 ± 0.023	1.43 ± 0.022
	Cortical	0.814 ± 0.019	0.883 ± 0.021*	+8.5	0.794 ± 0.021	0.800 ± 0.015
	Trabecular	0.445 ± 0.034	0.356 ± 0.019*	−20	0.391 ± 0.015	0.379 ± 0.014
PERI_C (mm)		4.26 ± 0.033	4.31 ± 0.038		4.21 ± 0.035	4.22 ± 0.033
ENDO_C (mm)		2.82 ± 0.024	2.74 ± 0.043		2.77 ± 0.039	2.78 ± 0.028
CRT_THK_C (mm)		0.230 ± 0.004	0.251 ± 0.006*	+8.9	0.228 ± 0.006	0.229 ± 0.003

* p ≤ 0.05 and ^† p ≤ 0.005 (both compared with vehicle-treated C57BL/6).