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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Placenta. 2008 Aug 8;29(9):784–789. doi: 10.1016/j.placenta.2008.06.013

Figure 2.

Figure 2

The effect on trophoblast cell death of villous explant culture at 20% (Normoxia) or 2% (Hypoxia) O2. In A, the TUNEL Index was determined during culture in medium alone or medium supplemented with 1 nM recombinant HBEGF at normoxia (N/HBEGF) or hypoxia (H/HBEGF). In B, 10 μg/ml CRM197 was added to the medium during culture at 20% O2 to antagonize HBEGF signaling. *, p<0.05, compared to control (0 h).