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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Dev Biol. 2008 Jul 9;321(2):407–419. doi: 10.1016/j.ydbio.2008.07.005

Fig. 3.

Fig. 3

The distribution of the growth plate markers in the Wnt1-Cre;Pkd1 presphenoidal synchondrosis is normal prior to its closure. (A) H&E staining of the parasagittal sections of control and mutant cranial base at P4 demonstrates a reduction in length of the Pkd1-deficient PSS prior to its closure. (B) H&E staining of the transverse sections of the control and mutant PSS at P6 shows premature closure for the mutant synchondrosis. (C-E) Expression pattern of the type X (C), type II (D) and Osteopontin in the P3 control and mutant PSS visualized by in situ hybridisation show no strong differences.