Temporal evolution of particle size (A) and polydispersity (B) in the presence of (•) PP1, (○) PP2, (▪) PP4, and (□) PP9, in liposomes composed of POPC (70 mol %)and cholesterol (30 mol %). Control (vesicles in absence of PFCs): vesicle size = 186.5 ± 15.8 nm, and polydispersity = 0.076 ± 0.031, over time period of 120 h. Three different stages described in text are indicated by I, II, and III.