TABLE 1.

Permeability Ratios for Cl⁻ relative to Li⁺, Na⁺, and Cs⁺ at 22°C for both WT and mutant P−2′▵ GlyR channels

Channel	PCl/PLi	PCl/PNa	PCl/PCs	Ion selectivity
WT GlyR	23.4 ± 2.8 (6)	10.9 ± 0.3 (32)	5.0 ± 0.5 (6)	Anion
P−2′▵ GlyR	6.0 ± 0.4 (7)	3.3 ± 0.2 (8)	1.9 ± 0.1 (7)	Anion

The values were averaged from permeability ratios determined using the GHK equation from individual dilution potential experiments, and are given as the mean ± SE, with the number of observations shown in parenthesis.