Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A 30 s IP3 pulse induces a large spike in PFK activity, followed for 10 min by large-amplitude ringing, in a single model islet. This results in large downward spikes in the cytosolic ATP concentration, which sets the phase of the compound electrical and Ca2+ oscillations. While the PFK activity is ringing, the model islets are synchronized.
