Table 4.

Adjusted caregiver QOL domain scores compared with general population control group*

WHOQOL-Bref domain	Corrected caregiver mean (SD) N = 120	General population Mean(SD) N = 136	T	Df	P	Effect size	95% C.I.
Physical health	11.3 (3.6)	11.1 (2.0)	0.6	254	0.5	0.08	- 0.17 – 0.32
Psychological health	16.9 (4.9)	17.7 (2.9)	1.5	254	0.1	0.19	- 0.06 – 0.44
Independence	15.3 (4.3)	15.7 (2.7)	0.9	254	0.3	0.12	- 0.13 – 0.36
Social relations	10.4 (3.8)	11.4 (2.2)	2.5	254	0.01	0.62	0.37 – 0.87
Environment	28.6 (6.2)	28.9 (4.5)	0.4	254	0.7	-	-
Spiritual	3.4 (1.4)	3.9 (0.8)	3.5	254	0.007	0.43	0.18 – 0.68
General facet health & QOL	7.7 (2.1)	8.3 (1.4)	2.8	254	0.005	0.35	0.11 – 0.60
Physical health:
RRMS (N = 103)	10.5 (2.1)**	11.1 (2.0)****	2.2	151	0.03	0.51	0.00 – 1.01
PMS (N = 17)	12.2 (2.9)
Independence:
RRMS (N = 103)	14.2 (2.4)***	15.7 (2.7)****	0.9	151	0.3	0.25	-0.26–0.75
PMS (N = 17)	16.4 (3.4)

* Caregiver's QOL domain scores were corrected for patient's depression (BDI) and disability (EDSS) scores

** Comparison: RRMS Vs PMS physical health: T = 2.9, df = 118, P = 0.004

*** Comparison: RRMS Vs PMS independence: T = 3.3, df = 118, P = 0.001

**** Comparison: PMS Vs general population control group