Fig. 1.

Podoplanin expression in a tooth germ of mouse incisor at the bell stage. Aggregated cells of the enamel organ lie above a condensation of ectomesenchymal cells, the dental papilla. The cervical loop where the outer enamel epithelium and the inner enamel epithelium join is observed at the apical side of the tooth germ. Reaction products with anti-podoplanin antibody are observed in the cervical loop, and in the odontoblast layer with the immunoreactivity to anti-nestin. H-E, Hematoxylin-Eosin staining. Bar=100 µm.