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. Author manuscript; available in PMC: 2008 Oct 31.
Published in final edited form as: Cell Immunol. 2005 Dec 6;237(1):68–75. doi: 10.1016/j.cellimm.2005.10.002

Table 1.

Bromelain treatment demonstrates no in vivo toxicity

Animal groups Weight (gm) BAL Total WBC (× 104) BAL EOS (× 104) BAL protein (μg/ml) Whole blood WBC (mm3) Histology PS score (grade 0-4)
Naïve-saline 18.3 ± 0.4 0.95 ± 0.2 0.8 ± 0.3 90 ± 12 2228 ± 257 <1.0
Naïve-bromelain (6mg/kg) 17.9 ± 0.3 0.87 ± 0.2 1.5 ± 0.2 123 ± 30 1775 ± 366 <1.0

All outcome measures were collected at the time of animal sacrifice. There were no significant differences when comparing the naïve-saline and naïve-bromelain treated groups (unpaired t test). Data represent means ± SEM with 6-8 animalscompared per group.