FIGURE 5.

Differential rescue of Jurkat cells ± MAT-IIβ expression by incrementally increasing l-Met levels in culture. Untransduced and V1302- and V1110-transduced Jurkat cells (5 × 10⁶) were cultured at 10 μm l-Met for 6 days, and then l-Met was raised to either 20 μm (A) or 50 μm (B). Viable cells were counted over 15 days, with the addition of fresh medium every 3 days. V1110 cells ceased to grow when l-Met was raised to 20 μm and exhibited diminished growth even at 50 μm.^*, p ≤ 0.05; ^**, p ≤ 0.01; ^***, p ≤ 0.001.