TABLE 3.
Sensitivity, specificity, and predictive valuesa of weekly RT-PCR and biweekly GM detection for the diagnosis of IA in 138 treatment episodes for 124 high-risk patients with hematological disorders
| Assay | Se | Sp | PPV | NPV |
|---|---|---|---|---|
| RT-PCR | ||||
| LSV | 100 (90.5.-100) | 96.7 (92.1-98.3) | 81.0 (58.9-89.7) | 100 (98.4-100) |
| SSVb | 76.5 (50.7-86.9) | 96.7 (91.1-98.3) | 81.3 (55.6-89.7) | 95.6 (89.5-97.8) |
| GM | 88.2 (65.5-93.1) | 95.8 (90.8-97.8) | 75.0 (51.2-85.8) | 98.3 (94.4-99.0) |
a
Data are percentages (95% confidence intervals).
b
Evaluated in 107 treatment episodes for 105 patients.