TABLE 2.
M. tuberculosis genotype families and associated patient characteristics in West Java
| Patient characteristica | Result for the following spoligotype familyb:
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| A (H) | B (T) | C (T) | D (LAM) | E (H) | F (EAI) | G (U likely H3) | H (U likely S) | I (Beijing) | Other | Total | |
| No. (%) | 41 (5) | 98 (12.1) | 43 (5.3) | 71 (8.7) | 40 (4.9) | 50 (6.2) | 37 (4.6) | 27 (3.3) | 268 (33.0) | 138 (17.0) | 813 (100) |
| Age (yr) | |||||||||||
| Median | 26.0 | 28.5 | 30.0 | 28.0 | 27.0 | 34.5 | 27.0 | 27.0 | 30.0 | 35.0 | 30 |
| IQR | 20.5-36.0 | 23.0-42.0 | 24.0-46.0 | 23.0-39.0 | 21.3-41.8 | 24.0-46.3 | 22.5-40.0 | 20.0-41.0 | 23.0-41.0 | 25.0-47.0 | 23.0-43.0 |
| Male | 43.9 | 58.2 | 48.8 | 56.3 | 52.5 | 52.0 | 54.1 | 48.1 | 49.3 | 50.7 | 51.4 |
| BCG scarc | 46.3 | 24.5 | 16.3 | 29.6 | 30.0 | 22.0 | 24.3 | 22.2 | 28.0 | 35.5 | 28.7 |
| Previous TB treatment | 12.2 | 16.3 | 4.7 | 8.5 | 10.0 | 20.0 | 10.8 | 18.5 | 9.7 | 12.3 | 11.7 |
| Disease localization | |||||||||||
| Extrapulmonary | 2.4 | 9.2 | 7.0 | 7.0 | 0.0 | 4.0 | 2.7 | 25.9 | 11.2 | 10.9 | 9.0 |
| Pulmonary | 97.6 | 90.8 | 93.0 | 93.0 | 100.0 | 96.0 | 97.3 | 74.1 | 88.8 | 89.1 | 91.0 |
| Drug resistanced | |||||||||||
| Isoniazid (R + I) | 17.1 | 14.3 | 11.6 | 7.0 | 17.5 | 14.0 | 10.8 | 11.1 | 13.1 | 9.4 | 12.3 |
| Isoniazid (R only) | 9.8 | 7.1 | 7.0 | 4.2 | 7.5 | 10.0 | 2.7 | 3.7 | 8.2 | 5.1 | 6.9 |
| Rifampin | 7.3 | 11.2 | 4.7 | 5.6 | 10.0 | 8.0 | 2.7 | 7.4 | 5.6 | 7.2 | 6.9 |
| MDR | 7.3 | 4.1 | 2.3 | 2.8 | 5.0 | 6.0 | 0.0 | 3.7 | 3.7 | 4.3 | 3.9 |
Except where otherwise indicated, each data point is the percentage of patients with the indicated characteristic. IQR, interquartile range; R, resistant; I, intermediate.
Given as the spoligotype family designation from this study (spoligotype family designation from SpolDB4).
Evaluated for 565 patients.
DST was successful for 694 isolates.