TABLE 1.
Serotype distribution and penicillin resistance of S. pneumoniae isolates from middle ear fluids of Japanese pediatric patients with AOM, based on age
| Serotype | No. (%) of isolates from indicated age group
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤2 yr
|
≥3 yr
|
All
|
||||||||||
| PSSP | PISP | PRSP | Total | PSSP | PISP | PRSP | Total | PSSP | PISP | PRSP | Total | |
| 1 | 1 (1.5) | 1 (1.5) | 1 (0.6) | 1 (0.6) | ||||||||
| 3 | 3 (2.8) | 3 (2.8) | 13 (19.1) | 13 (19.1) | 16 (9.1) | 16 (9.1) | ||||||
| 4 | 1 (1.5) | 1 (1.5) | 1 (0.6) | 1 (0.6) | ||||||||
| 6A | 5 (4.7) | 6 (5.6) | 3 (2.8) | 14 (13.1) | 1 (1.5) | 1 (1.5) | 2 (2.9) | 6 (3.4) | 6 (3.4) | 4 (2.3) | 16 (9.1) | |
| 6B | 7 (6.5) | 9 (8.4) | 3 (2.8) | 19 (17.8) | 1 (1.5) | 1 (1.5) | 8 (4.6) | 9 (5.1) | 3 (1.7) | 20 (11.4) | ||
| 7F | 1 (0.9) | 1 (0.9) | 1 (0.6) | 1 (0.6) | ||||||||
| 9V | 2 (2.9) | 2 (2.9) | 2 (1.1) | 2 (1.1) | ||||||||
| 9N | 1 (0.9) | 1 (0.9) | 1 (0.6) | 1 (0.6) | ||||||||
| 10A | 3 (2.8) | 3 (2.8) | 3 (4.4) | 3 (4.4) | 6 (3.4) | 6 (3.4) | ||||||
| 11A | 1 (0.9) | 1 (0.9) | 1 (1.5) | 1 (1.5) | 2 (1.1) | 2 (1.1) | ||||||
| 12F | 1 (0.9) | 1 (0.9) | 1 (1.5) | 1 (1.5) | 2 (1.1) | 2 (1.1) | ||||||
| 14 | 1 (0.9) | 7 (6.5) | 2 (1.9) | 10 (9.3) | 3 (4.4) | 6 (8.8) | 1 (1.5) | 10 (14.7) | 4 (2.3) | 13 (7.4) | 3 (1.7) | 20 (11.4) |
| 15B | 2 (1.9) | 2 (1.9) | 1 (1.5) | 1 (1.5) | 2 (2.9) | 1 (0.6) | 3 (1.7) | 4 (2.3) | ||||
| 18C | 2 (1.9) | 2 (1.9) | 1 (1.5) | 1 (1.5) | 3 (1.7) | 3 (1.7) | ||||||
| 19A | 1 (0.9) | 1 (0.9) | 4 (5.9) | 4 (5.9) | 5 (2.9) | 5 (2.9) | ||||||
| 19F | 11 (10.3) | 13 (12.1) | 24 (22.4) | 4 (5.9) | 6 (8.8) | 10 (14.7) | 15 (8.6) | 19 (10.9) | 34 (19.4) | |||
| 22F | 1 (1.5) | 1 (1.5) | 1 (0.6) | 1 (0.6) | ||||||||
| 23F | 1 (0.9) | 5 (4.7) | 12 (11.2) | 18 (16.8) | 5 (7.4) | 3 (4.4) | 8 (11.8) | 1 (0.6) | 10 (5.7) | 15 (8.6) | 26 (14.9) | |
| Group 23 | 2 (1.9) | 1 (0.9) | 3 (2.8) | 3 (4.4) | 3 (4.4) | 5 (2.9) | 1 (0.6) | 6 (3.4) | ||||
| non23 | 2 (1.9) | 2 (1.9) | 4 (3.7) | 1 (1.5) | 2 (2.9) | 1 (1.5) | 4 (5.9) | 3 (1.7) | 4 (2.3) | 1 (0.6) | 8 (4.6) | |
| Total | 29 (27.1) | 44 (41.1) | 34 (31.8) | 107 (100) | 34 (50.0) | 22 (32.4) | 12 (17.6) | 68 (100) | 63 (31.2) | 66 (32.7) | 46 (22.8) | 175 (100) |