TABLE 3.

Correlation between data for qPCR-1 and qCx for BAL fluid and lung tissue in experimental pulmonary zygomycosis

Organism	Sample type	Correlation coefficienta	P valued	Total no. of samples	No. of samples positive by qPCR but negative by qCx
R. oryzae	BAL fluid	0.61	0.17	7	1
R. oryzae	Lung tissueb	0.55	<0.01	35	2
R. microsporus	BAL fluid	−0.49	0.37	6	0
R. microsporus	Lung tissueb	0.65	<0.01	34	1
M. circinelloides	BAL fluid	−0.26	0.47	10	0
M. circinelloides	Lung tissueb,c	0.70	<0.01	30	2
C. bertholletiae	BAL fluid	0.63	0.01	15	5
C. bertholletiae	Lung tissueb	0.68	<0.01	90	4

^aCalculated by the Spearman rank correlation method (Instat 3; Graphpad Software).

^bOnly lung tissue samples containing pathological evidence of infarction were processed.

^cOne sample was negative by both qCx and qPCR.

^dA P value of ≤0.05 is considered to be significant.