FIG. 1.

Multiple sequence alignment of the pediocin-like bacteriocins (1, 5-7, 9, 13-15, 17, 18, 24, 25, 27, 29-31, 34, 35, 38-40, 45, 48, 49-51, 54, 55, 58). The common YGNGV/L (“pediocin box”) motif is shown in bold. The residues in the C-terminal half are colored as follows: Asn, Asp, Gln, and Glu are in green; Ile, Leu, and Val are in purple; Trp, Tyr, and Phe are in black; Cys is in gray; Ala and Gly are in yellow; Arg, Lys, and His in blue; Ser and Thr are in red; Pro is in white; and Met is in dark blue. Note that in numbering the residues (as indicated above the sequences), residue number 2 before the well-conserved YGNGV motif is in all cases referred to as residue 1, since this residue is the first residue in most—but not all—of the peptides.