Skip to main content
. Author manuscript; available in PMC: 2009 Jul 4.
Published in final edited form as: J Mol Biol. 2008 May 2;380(2):303–312. doi: 10.1016/j.jmb.2008.04.061

Figure 4.

Figure 4

The PHD-H3K4me3 binding stabilizes ING1 at the methylated chromatin. Intracellular localization of the wild type (WT) and mutant EGFP-ING1 PHD fingers (green) in HeLa cells. The cells were stained with anti-H3K4me3 antibodies (red) and DAPI (blue). The ratio of the nuclear vs. cytoplasmic EGFP [2.28 (wild type), 1.92 (N216S), 1.75 (V218I) and 1.84 (G221V)] was obtained by averaging the fluorescence intensity in ten or more cells.