Figure 2.

Current traces comparing receptors formed from different transfections: α1β2, αβtan+α1, α1β2γ2S 1:1:10, αβtan+γ2S, and αβtan+γ2L. GABA (10 mm) pulse durations were 20 ms (top row, A, D), 2000 ms (middle row, B, E) and 20,000 ms (bottom row, C, F). Differences in desensitization are more clearly seen in longer (2000 and 20,000 ms) pulses, and comparisons of deactivation are visible in short (20 ms) traces and in longer traces when normalized to the current at the end of the pulse (middle row, insets). One example of αβtan+γ2L is shown for comparison in C (gray).